AOAC 2017 Annual Meeting Preliminary Program

3:30 PM – 5:00 PM TDRM Symposium: CRMs & RMs — What is the Difference and What Does My Lab Need? Reference materials (RMs) are essential tools for the analytical laboratory. Certified reference materials (CRMs) and RMs are used to assess the quality of measurements and the applicability of methods. However, end users often have questions on how to use a CRM, how to know that they have gotten the “correct” answer for a specific measurand, and “Why does it take so long to produce a CRM?”. Even with answers to these questions, it is not always possible to find a CRM or RM with the “perfect” matrix. End users are left with the task of making their own in-house materials and questions about how to do it. In this session, the design, production, and certification of CRMs will be discussed alongside the selection and use of CRMs. Finally, we will discuss the value of producing an in-house reference material and how to use CRMs for value assignment of in-house reference materials. CO-CHAIR: Laura Wood, National Institute of Standards and Technology CO-CHAIR: Catherine Rimmer, National Institute of Standards and Technology • Mitzi Rettinger, Cerilliant Corporation The Importance of Certification and Preparation of Reference Materials: Dietary Supplements and Cannabis • Håkan Emteborg, European Commission – Joint Research Centre Preparation of a PM2,5-like Reference Material Mimicking Atmospheric Fine Dust: How Difficult Can It Be and Why Did It Take So Long? • Pearse McCarron, National Research Council Canada The Complimentary Roles of Certified and In-House Reference Materials for Biotoxin Measurements in Seafood • Eric Gordon, Covance Laboratories Inc. The Application of Certified Reference Materials and In-House Reference Material in the Quality Control, Validation and Harmonization of Methods across Multiple Test Sites Challenges in the Shift to Color Additives from Natural Sources: Regulation and Chemistry Color additives (both synthetic and those derived from natural sources) used in food and cosmetic products in the United States and internationally are often complex formulations. In the changing world of consumer perception of color additives, there has been a shift to color additives from natural sources and has impacted the regulatory world of color additives. There is a need for a global stage where science based data, knowledge, and information can be shared. This AOAC Scientific Session provides initial briefings that speak to the challenges on both

the regulatory and analytical scientific fronts and to further develop our AOAC Community on Cosmetics and Color Additives. CHAIR: Bhakti Petigara Harp, U.S. Food and Drug Administration, Center for Food Safety and Applied Nutrition • George Pugh, The Coca-Cola Company Naturally Sourced Colors: Proactive Strategies to Support their Safety • Carol Locey, Kalsec

Advances in Natural Red Colors from Beets • Monica Giusti, The Ohio State University The Chemistry of Anthocyanins: Diverse Structures for a Colorful World

• Maria Bastaki, International Association of Color Manufacturers Safety Data Requirements for Color Additives from Natural Sources Novel Analytical Approaches to Manufacturing QC in the Dietary Supplement and Food Industries The average consumer’s awareness and expectations of the quality and nutritional content of their favorite foods, beverages and dietary supplements are certainly higher than ever before. Addressing both the sensitivity these customers have for the composition of dietary supplements and foods as well as an increasingly expansive regulatory landscape presents a variety of scientific and operational challenges for manufacturers around the world. Due to the natural sample complexity, chromatography and mass spectrometry techniques are desirable in both research and QC laboratories. Mass detection is widely recognized as a reliable technique to derive more meaningful information from food and dietary supplement samples and is an orthogonal, complementary technique to optical detection. In order to offer laboratories the opportunity to capture the benefits of mass detection without the challenges typically associated with mass spectrometers; recent advances in technology have focused on improving instrument usability and robustness. Scientists now have the ability to generate information-rich mass spectral data which complements data from optical detectors such as photo diode array (PDA), tunable ultraviolet/ visible (TUV), evaporative light scattering (ELS), and fluorescence (FLR). In this session, four industry leaders will share their experiences and approaches to testing dietary supplements and food ingredients, with a focus on analytical techniques that show great potential in solving today’s scientific and operational challenges in the industry. CO-CHAIR: Joe Romano, Waters Corporation CO-CHAIR: Amit Chandra, AMWAY Nutritional Supplements • Bertil Nshime, AMWAY Mass Detection for Routine QC Analysis of Beauty and Nutrition Products • Mekile Vuyani Analysis of Water Soluble Vitamins in Animal Feed and Human Food • Jane Guido Quantitation of Capsaicinoids by UPLC/MS Using Single Quadrupole Mass Spectrometry in the QC Environment • James Traub, Herbalife International of America Inc. Benefits of Mass Detection for the Routine Analysis of

20 WWW.AOAC.ORG  301.924.7077