AOAC 2017 Annual Meeting Preliminary Program

• Konstantinos Konstantinidis, Georgia Institute of Technology Metagenomic Investigation of Foodborne Outbreaks • Sam Minot, One Codex Validating Microbial Metagenomics using Standardized, Reproducible Methods with One Codex Worldwide Perspectives on Contaminants Testing in Food and Environmental Samples Using Advanced Analytical Techniques We have gathered scientist from around the world in one session to get a fully worldwide perspective of food and environmental testing using newer technologies. In this session you can see how scientists from Europe, Asia, Australia and North America utilize powerful modern technologies on residue testing and gain insight on how this can help you with your scientific endeavors. CO-CHAIR: Ping Wan, Office of Indiana State Chemist CO-CHAIR: Steven Moser, Oklahoma Department of Agriculture, Food & Forestry • Walter Hammack, Florida Department of Agriculture and Consumer Services High Resolution Mass Spectrometry Strategies for Targeted and Non-Targeted Analysis in Food Samples Food and Environmental Contamination Analysis: Nice to Have and Necessary Today, an Australian Perspective • Amadeo Fernandez-Alba, University of Almeria High Resolution Mass Spectrometry Experiences from the European Union Reference Laboratory for Pesticide Residues in Fruits and Vegetables 10:15 AM – 11:45 AM What’s New in Carbohydrates? Functional Carbohydrate Ingredients and Dietary Fiber Regulation Carbohydrates are the most abundant group of natural products. They serve as energy storage molecules (starch, glycogen), and structural components (cellulose, chitin) in plants and living organisms. Carbohydrates are present in all types of cell walls and cell membranes, playing important roles in physiological and pathological processes, such as fertilization, immunity, cancer, etc. They are also critical to many other biological processes, such as DNA/RNA formation and protein glycosylation. Furthermore, carbohydrates are unambiguously one of the major macronutrients for human diet. The dietary guidelines recommend 45–65% of a healthful diet comes from carbohydrates. Carbohydrates are not only an important energy source but also, as dietary fiber, provide other health benefits by promoting health and well- being or reducing the risk of disease. In the carbohydrate session, we will cover topics around dietary fiber and emerging functional carbohydrate aspects, including their definition, benefits and functions, and analytical methods. We will discuss the current analytical progress on sialic acid, chondroitin and GAGs, dietary fiber and human milk oligosaccharides. CO-CHAIR: Xun Yan, AMWAY CO-CHAIR: Jon Devries, Medallion Laboratories/General Mills • Mingchih Fang, Taiwan Food and Drug Administration High-Resolution Mass Spectrometry in Food Analysis: Real Case Experiences from Taiwan FDA • Robert Trengove, Murdoch University

WEDNESDAY, SEPTEMBER 27, 2017 8:15 AM – 9:45 AM

Committee on Statistics Symposium: Ideas for Target Measurement Uncertainty, Intermediate Precision, and Collaborative Studies — Review and Meta-Analysis Members of the AOAC Committee on Statistics will present statistics supporting target measurement uncertainty and the Analytical Target Profile as described in recent USP articles as it relates to the upcoming revision of the ISO 17025. Furthermore, there will be a presentation on intermediate precision, its generalization and how to design a study for its measurement. Additionally, a review of quantitative collaborative studies for a chemical analyte published in J. AOAC from 2000 to 2016 were identified and the reported statistical results tabulated. A meta-analysis of the results was performed and an evaluation made of possible performance requirements based on tolerance limits of the observed population of studies and compared to the HORRAT system will also be presented. CHAIR: Sidney Sudberg, Alchemist Labs • Jane Weitzel, Consultant Statistics to Support Target Measurement Uncertainty and the Analytical Target Profile as Described in Recent USP Articles • Paul Wehling, Medallion Labs/General Mills Intermediate Precision: Its Generalization and How to Design a Study for its Measurement • Sidney Sudberg, Alchemist Labs A Systematic Review and Meta-Analysis of Quantitative Chemical Collaborative Studies Published in J. AOAC from 2000 to 2016 Based on the Logarithmic metamer pC Applications of Metagenomics for Food Safety Genomic technologies are now frequently used for the characterization of foodborne pathogens, and have been beneficial in the identification of sources of foodborne outbreaks. While such investigations typically rely on the genomic characterization of bacterial isolates, metagenomic analysis of more complex communities is proving to be a valuable tool supporting food production and food safety objectives. Applications of metagenomics include: (1) study of complex enrichment culture growth dynamics to gain a better understanding of factors influencing growth of pathogens in food enrichment broths leading to improved microbiological methods, (2) characterization of bacterial communities in food commodities and food production environments to identify signals of potential problems, enabling early interventions to avoid pathogen contamination of food commodities and (3) Detection of pathogens in foodborne outbreak investigations that could not be cultured using traditional means, enabling characterization of the etiological agents associated with the outbreak. This session will present some of the emerging uses for metagenomics in food safety and describe bioinformatics methods for metagenome analysis enabling participants to gain a better understanding of how metagenomics technologies can be applied to improve food safety outcomes. CO-CHAIR: Catherine Carrillo, Canadian Food Inspection Agency (CFIA) CO-CHAIR: Irene Iugovaz, Health Canada • Karen Jarvis, U.S. Food and Drug Administration Pathogen Detection and Food Microbiome Characterization Using a Metagenomics Approach

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