AOAC CASP Meeting - MYM 2020

G UIDELINES FOR S TANDARD M ETHOD P ERFORMANCE R EQUIREMENTS

AOAC O FFICIAL M ETHODS OF A NALYSIS (2012)

Appendix F, p. 6

Table A1. Performance requirements

Classi ¿ cations of methods a

Quantitative method

Qualitative method

Trace or contaminant c

Main component b

Trace or contaminant c

Main component b

Identi ¿ cation method

Parameter Single-laboratory validation Inclusivity/selectivity Exclusivity/cross-reactivity Environmental interference Laboratory variance

Applicable range Bias d

Inclusivity/selectivity Exclusivity/cross-reactivity Environmental interference Laboratory variance

Inclusivity/selectivity Exclusivity/cross-reactivity Environmental interference

Applicable range Bias d

Precision Recovery Limit of quantitation (LOQ)

Precision Recovery LOQ

POD at AMDL f

Probability of identi ¿ cation (POI)

Probability of detection (POD) e

Reproducibility

RSD R or target measurement uncertainty

RSD R or target measurement uncertainty

POD (0) POD (c) Laboratory POD g

POD (0) POD (c) Laboratory POD g

POI (c)

Laboratory POI

a See Annex B for additional information on classi ¿ cation of methods. b • 100 g/kg. c <100 g/kg. d If a reference material is available. e At a critical level. f AMDL = Acceptable minimum detection level. g LPOD = CPOD.

© 2012 AOAC INTERNATIONAL