AOAC CASP Meeting - MYM 2020
56 57
4. Method Performance Requirements :
Limit of Quantitation (LOQ)
≤ 10 ppb (μg/kg)
Reproducibility (RSD R )
Repeatability (RSD r )
Range
Recovery
>100 ppb to 1 ppm ≥ 10 ppb to 100 ppb > 1 ppm to 10 ppm
15% 11% 7.3%
32% 16%
60% - 115% 80% - 115% 80% - 115%
8%
58 59 5. System suitability tests and/or analytical quality control: 60
61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91
Suitable methods will include blank check samples, and check standards at the
lowest point and midrange point of the analytical range.
6. Reference Material(s):
A certified reference material should be used when available. Internally produced reference materials may be used for a variety of cannabis products such as plant material, concentrates, and finished products until reference material is made available by an internationally-recognized organization such as Institute for Reference Materials and Measurements (IRMM) or United States National Institute of
Standards and Technology (NIST).
7. Validation Guidance & References :
Recommended level of validation: Official Methods of Analysis SM
USP <233>
8. Maximum Time-To-Result : No maximum time.
Table 1: Optional Elements Not Frequently Required
• Antimony • Barium • Chromium • Copper
CAS No. 744-36-0 CAS No. 744-39-3 CAS No. 18540-29-9 CAS No. 744-50-8 CAS No. 7440-02-0 CAS No. 7440-22-4 CAS No. 7782-49-2 CAS No. 7440-66-6
• Nickel • Silver
• Selenium
• Zinc
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