AOAC CASP SMPRs for Comment
102 103 104 105 106 107 108
9. Maximum Time-To-Result: None
Table 1: Residual Solvents
Table 1: List of Residual Solvents and Targeted LOQs
Proposed Target LOQ (ppm)
Analytical Range
Concentration Limit (ppm)
Lower
Upper
1 2
1 2
30 60
Class 1 Residual Solvents*
2
Benzene
4
4
4
120
Carbon tetrachloride
5
5
5
150
1,2-Dichloroethane 1,2-Dichloroethane
1870
8
8
8
240
1,1-Dichloroethene
1870
1,1-Dichloroethene 1,1,1-Trichloroethane
1500
1500
1500
45000
Class 2 Residual Solvents* Acetonitrile
410
410
12300
410
acetonitrile
6
360
360
10800
Chlorobenzene
360
60 70
60 70
1800 2100
Chloroform
60 70
Cumene
3880 1870
3880 1870
116400
Cyclohexane
3880 1870
56100
1,2-Dichloroethene 1,2-Dimethoxyethane N,N-Dimethylacetamide N,N-Dimethylformamide
100
100
3000
100
1090
1090
32700 26400 11400
1090
880 380 160 620 220 290
880 380 160 620 220 290
880 380 160 620 220 290
1,4-Dioxane
4800
2-Ethoxyethanol Ethylene glycol
18600
6600 8700
Formamide
Hexane
n-hexane Methanol Methanol
60
3000
3000
90000
3000
400
50 50
50 50
1500 1500
2-Methoxyethanol Methylbutylketone Methylcyclohexane
50 50
1180
1180
35400
1180
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