AOAC Final Action Methods in 2017

1118  C ampos G iménez & M artin : J ournal of AOAC I nternational V ol . 101, N o . 4, 2018

Soo Hui Chooi, Bee Lin Tan, and Lai Kuan Yap, Nestlé Quality Assurance Center (Shah Alam, Malaysia) Scott Christiansen and Lucas LeCours, Perrigo Nutritionals (Georgia, VT) Elaine Marley, R-Biopharm Rhône Ltd (Glasgow, Scotland) Gerald Larkin and Adrienne Mcmahon, Wyeth Nutrition (Askeaton, Ireland) Diane Labitan and Rodolfo Norriel Nipales, Wyeth Nutrition (Laguna, Philippines) Hui Xin Lim and Anna Chua, Wyeth Nutrition (Singapore). (1) Institute of Medicine Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate, Other B Vitamins, and Choline (1998) Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline . National Academies Press, Washington, D.C. (2) CODEX (1981) Standard for Infant Formula and Formulas for Special Medical Purposes Intended for Infants , Codex Alimentarius Commission, Rome, Italy, No. 72, 1–21 (3) Martin, F., Campos Giménez, E., & Konings, E. (2016) J. AOAC Int. 99 , 1–7 (4) Official Methods of Analysis (2005) 18th Ed. AOAC INTERNATIONAL, Gaithersburg, MD, Method 986.23 (5) Official Methods of Analysis (2005) 18th Ed. AOAC INTERNATIONAL, Gaithersburg, MD, Method 2011.16 (6) Official Methods of Analysis (2005) 18th Ed. AOAC INTERNATIONAL, Gaithersburg, MD, Method 2011.09 (7) Official Methods of Analysis (2005) 18th Ed. AOAC INTERNATIONAL, Gaithersburg, MD, Method 2011.10 (8) Official Methods of Analysis (2005) 18th Ed. AOAC INTERNATIONAL, Gaithersburg, MD, Method 2011.08 (9) Official Methods of Analysis (2005) 18th Ed. AOAC INTERNATIONAL, Gaithersburg, MD, Method 2014.02 (10) ISO 20634:2015: Infant formula and adult nutritionals- Determination of Vitamin B12 by Reversed Phase High Performance Liquid Chromatography (RP-HPLC) , International Organization for Standardization, Brussels, Belguim (11) Campos-Giménez, E., Fontannaz, P., Trisconi, M.J., Kilinc, T., & Gimenez, C. (2008) J. AOAC Int. 91 , 786–793 (12) Campos-Giménez, E., Fontannaz, P., Trisconi, M.J., Kilinc, T., Gimenez, C., & Andrieux, P. (2012) J. AOAC Int. 95 , 307–312 (13) Campos-Giménez, E. (2014) J. AOAC Int. 97 , 1397–1402 (14) Official Methods of Analysis (2005) AOAC INTERNATIONAL, Gaithersburg, MD, Appendix D (15) Appendix 1: AOAC SMPR (2012) J. AOAC Int . 95 , 293, doi:10.5740/jaoac.int.11-0441 References

Conclusions

The precision figures obtained during this collaborative study show that Official Method 2014.02 complies with the requirements set in the corresponding SMPR, and, thus, it is fit for purpose for the analysis of vitamin B 12 (cyanocobalamin) in infant formula and adult/pediatric nutritionals. Additionally, the accuracy of the method was demonstrated by agreement of results on SRM with reference values. Both HPLC or UHPLC conditions have proven to be of equivalent performance, allowing for method applicability in all laboratories. These data were submitted to the ERP for review at theAOAC International annual meeting held September 2016 in Dallas, Texas. The ERP determined that the data presented met the SMPR set by SPIFAN and, hence, recommended the method to be granted Final Action status. We would like to specially thank Colleen Fehrenbach at Covance Laboratories (Madison, WI) for the dispatch of the samples to the participants. We greatly thank the following participants and their associates for their valuable contributions to the study: Isabelle Malaviole, Laboratoire Aquanal (Pessac, France) George Joseph, Asure Quality (Auckland, New Zealand) John Austad and Andrew Ruosh, Covance Laboratories (Madison, WI) Sabine Meng-Jensen and Susan Nielsen, Eurofins Steins Laboratorium A/S (Vejen, Denmark) Wenjuan Elaine Jobgen and Kai Liu, Eurofins Scientific, Inc. (Des Moines, IA) Michael Jones, Mumtaz Dole, Peter White, Brendon Gill, and Harvey Indyk, Fonterra (Waitoa, New Zealand) Estela Kneteeman, Instituto Nacional de Tecnología (Buenos Aires, Argentina) Jean-Luc Deborde and Fabrice Arella, Laboratoire SCL (Illkirch, France) Carrie Otto, Guy Weerasekera, and Jen Frueh, Mead Johnson Nutrition (Evansville, IN) Sneh Bandhari and Tiffany Gallegos, Merieux NutriSciences (Crete, IL) Roy Nijman and Ton Noorloos, Nestlé Quality Assurance Center (Nunspeet, The Netherlands) Greg Jaudzems, Nestlé QualityAssurance Center (Dublin, OH) Acknowledgments

Downloaded from https://academic.oup.com/jaoac/article-abstract/101/4/1112/5654048 by AOAC Member Access user on 05 May 2020