AOAC GFA Stakeholder Program Meeting Book (August 27, 2023)

Allergen Community Topics

• Working with Difficult Matrices (foods that gel up when adding buffers) • Limitations to ELISA methods, cross-reactivity, intereferences, etc. • Multiplexing Assays • End user benchmark standard for third party labs (and for end users in production facilities); Guidance documents for customer verification/validation; Timeline for end user guidance • Timeframe for kit manufacturers to re-validate current AOAC methods to new guidelines • Method validation guidance for food allergen detection/quantification by LC-MS/MS - Similar but more detailed to EU standard 17644. • Scientific programming proposals for the 2024 annual meeting • How to increase the number of research posters related to allergens/gluten at annual meetings • Education and training for method developers, laboratories and food manufacturers • New methods for allergens analysis • International Reference Materials for Allergens • Establishment of Reference Methods • Establishment of Detection/Quantification Limits for each allergen • The impact of proposed allergen threshold levels on analysis • Understanding of the New FDA guidance: Sec. 555.250 Major Food Allergen Labeling and Cross-contact Draft Compliance Policy Guide