AOAC GFA Stakeholder Program Meeting Book (August 27, 2023)

Current Definition

VIM4 Second Committee Draft Definition intermediate precision conditions of measurement intermediate precision conditions specified conditions of measurement, where measured values are obtained by replicate measurements with the same measurement method, on the same or similar objects over an extended period of time in the same laboratory EXAMPLE 1 Intermediate precision conditions applied to measurement results obtained on internal measurement quality control materials in a laboratory over a stated period of time to monitor the quality of the measurements. EXAMPLE 2 Repeated PCR or ELISA measurements of the same object carried out under intermediate precision conditions if multiple 96-well-plates are used. NOTE 1 The extended period of time mentioned in the definition is intended to be long enough to allow for changes in the specified conditions. NOTE 2 The specification of an intermediate precision condition should include what the changes in conditions are, to the extent practical.

3.15 Intermediate precision conditions: Conditions where test results or measurement results are obtained with the same method, on identical test/measurement items in the same test or measurement facility, under some different operating condition. • There are four elements to the operating condition: time, calibration, operator and equipment.