AOAC GFA Stakeholder Program Meeting Book (August 29, 2021)

Single Laboratory Validation (Method Developer Study) • Calibration Fit Study o Description of calibration curve regression model/curve fitting approach o Verify appropriate fit across calibration range • Matrix Study Design Discussions

Study Designs: Quantitative Methods

o Precision o Recovery

o LOD o LOQ • Selectivity Discussions

o Suggested categories and foods o Minimum numbers of foods/ingredients, categories



• Subgroup on important sources of variation for allergen method validation

• Study design requirements o Quantitative o Qualitative o Support end user expectations

Next Steps and Future Directions

• Guidance on environmental samples

• Guidance on incurred foods (coordinated with gluten working group)



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