AOAC GFA Stakeholder Program Meeting Book (March 15, 2023)

Major Updates from Current Appendix M

• Guidance for both qualitative and quantitative methods • Reporting units in line with risk assessment work o mg total protein from the allergenic source/kg matrix • Requirement for incurred food matrices (in line with SMPRs) and guidance on preparation • Detailed instructions, R code, and examples of statistical analysis procedures o Nested study designs: Estimation of repeatability standard deviation and intermediate precision standard deviation

o LOD o LOQ

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