AOAC GFA Stakeholder Program Meeting Book (March 17, 2021)

Gluten

X General definition: Protein fraction of any grain that is insoluble in water and 0.5M NaCl X Regulatory Definition: Protein fraction of wheat, rye, barley (and in some countries, oats) that is insoluble in water and 0.5M NaCl, and to which some persons are intolerant* X Immune response to gluten can lead to an autoimmune reaction to an intestinal enzyme, tissue transglutaminase, resulting in intestinal damage = Celiac Disease X ~1% of the population in North America and Europe has CD *Adapted from Codex Stan 118-1979

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Gluten

X It has threshold s X 20 ppm in countries that follow Codex X “Not detected” in Australia/New Zealand (includes oats) X 10 ppm in Japan and Argentina X 5 ppm in Chile X There are several methods X Antibody-based (ELISA and LFD)

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