AOAC Gluten Quantitative Validation Guidance-Round 1(Nov 2023)

NOTE 1 Reproducibility may be evaluated by replicate measurements on similar objects, provided variability amongthe objects is negligible. NOTE 2 Relevant statistical terms are given in ISO 5725-1 and ISO 5725-2 [13].

Current Definition

VIM4 Second Committee Draft Definition

3.31 Reproducibility Conditions: Conditions where independent test results are obtained with the same methods on equivalent test items in different laboratories with different operators using separate instruments.

reproducibility conditions of measurement reproducibility conditions specified conditions of measurement, where measured values are obtained by replicate measurements on the same or similar objects in different laboratories by different operators using different measuring systems EXAMPLE Reproducibility conditions applied to collaborative study of the measurement procedure, organized by several laboratories. In this case the same measurement procedure is used by all laboratories. NOTE 1 In some cases the different laboratories may use different measurement methods. NOTE 2 The specification of reproducibility conditions should include all changes in conditions of measurement in different laboratories, that are significant for explanation of the observed spread of measured values.

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