AOAC ISPAM Quant. Micro Acceptance Criteria 6-28-18

AOAC INTERNATIONAL International Stakeholder Panel on Alternative Methods (ISPAM)

Quantitative Microbiology Method Validation Acceptance Criteria Working Group Meeting Thursday, June 28, 2018 (2:00PM Eastern US) Co-Chairs: Patrick Bird (Q Laboratories, Inc.) Patrice Arbault (BioAdvantage & Nexidia)

I. Review of How We Got Here II. Review of Priority Sequence

1. Difference of Means (Acceptance criteria) a. Indicator organism vs. pathogens b. Principle of the technology 2. Number of Out of Range Levels Per Assay a. Recommendations for dealing with discordant results 3. Determine Acceptance Criteria for Low Inoculation Level Replicates III. Overview of Data Mining IV. Action Items

Draft meeting agenda is subject to change w/out notice