AOAC Midyear Meetng - Acrylamide WG

Case 2: Selectivity of the Sample Preparation

Method based on FDA

Chromatographic profile of m/z 72 → 55 in a cocoa extract analyzed with Methods B and C.

B

Method

C

Method

Discrepancies up to x20 in cocoa in case of insufficient sample prep.

Different extent of clean-up