AOAC OMA# 2011.06 Final Action Review-OMB

ERP SUMMARY FOR FIRST TO FINAL ACTION METHOD RECOMMENDATION

AOAC No.  OMA# 2011.06  Total Folates in Infant Formula and Adult Nutritionals by Trienzyme Extraction and  UPLC‐MS/MS Quantitation

GUIDANCE FOR AOAC ERPS ‐ APPENDIX G 1 Considered? Comments/Reference if applicable Method Applicability  Yes  Applicable for determination of total folate  contents in infant formula and adult  nutritionals  ERP First Action to Final Action  recommendations & improvements  Yes  Draft Final Action method reviewed by ERP Yes  Via e‐Ballot  Safety Concerns  No  ReferenceMaterials  Yes  NIST SRM 1869  Single Laboratory Validation  Yes  Reproducibility/Uncertaintyand  Probability of Detection  Yes  Comparison to SMPR ( SMPR criteria met?) Yes  Feedback from Users of Method  Yes 

DOCUMENTATION  (see Methods book ) 

Comments

Available?

Part of the ERP Review and Discussions 

Safety Evaluation  ReferenceMaterials 

Yes  Yes  SLV  Yes  Yes  Yes  Yes  Yes  No  Yes 

NIST SRM 1869 

Published in OMA and in Journal  Based on OMA, Appendix L 

SLV or PTM 

Approved Validation Protocols 

Statistics Review 

  Part of the ERP Review and Discussions 

2011.06 

Method Published in OMA 

SMPR 

Method Performance vs SMPR criteria 

Feedback Information  Additional Recognition(s) 

ERP Reports 

March 18, 2015  September 26, 2017 

Journal of AOAC INTERNATIONAL VOL. 95, NO. 6,  2012  Journal of AOAC INTERNATIONAL VOL. 101, NO.  6, 2018 

Manuscript(s) Published in JAOAC 

Yes 

ERP Method Recommendation   (Final Action/Repeal/Continuation) 

Yes 

Final Action 

1 Official Methods of Analysis of AOAC INTERNATIONAL , Appendix G: Procedures and Guidelines for the Use of AOAC Voluntary Consensus Standards  to Evaluate Characteristics of a Method of Analysis, p.3 “ First Action to Final Action Methods: Guidance for AOAC Expert Review Panels.”