AOAC OMB Meeting Book 2-10-16

AOAC OMB Meeting

MEMORANDUM 

Date:   To:  From:   Subject: 

February 10, 2016  Official Methods Board  Scott Coates, AOAC Chief Scientific Officer  Item II. b.   Updating Appendix F 

BACKGROUND 

Appendix F: Guidelines for Standard Methods Performance Requirements (SMPR) was drafted in the  2009 – 2010 timeframe. Since 2010 AOAC has developed and adopted more than 60 SMPRs.  The SMPR  process has evolved since 2010 and some of the descriptions of processes have become obsolete, and  frankly some sections are not needed any more.  A revised, streamlined version of Appendix F is  attached as attachment 1.  An original Appendix F is attached as attachment 2 for reference.  1) Most of the proposed changes are sections that have been removed from the narrative descriptions in the first 4 pages.  An outdated Figure 1 has been replaced with a schematic that better represents the process as it occurs today. 2) The term “Intermediate repeatability/reproducibility” is added to table A1, defined in table A2, and evaluation recommendations provided in table 3. 3) The term ”LOQ” replaced by “Limit of determination (LOD)” in table A1 4) Question for OMB:  the Guideline identifies “bias” as one of recommended parameters, but “bias” has never been used in an SMPR.  The terms “accuracy” or “recovery” are routinely used in SMPRs. Should we recommend “bias” to the working groups now working on SMPRs?  Or should we replace “bias” in Appendix F with “accuracy” or “recovery”? Discussion 

February 10-11, 2016

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