AOAC OMB Meeting Book 2-10-16

AOAC OMB Meeting

AOAC O FFICIAL M ETHODS OF A NALYSIS (2012)

G UIDELINES FOR S TANDARD M ETHOD P ERFORMANCE R EQUIREMENTS Appendix F, p. 11

Figure A1. Relationship between precision versus bias (trueness). Trueness is reported as bias. Bias is defined as the difference between the test results and an accepted reference value.

Figure A2. Relationship between LOD and LOQ. LOD is defined as the lowest quantity of a substance that can be distinguished from the absence of that substance (a blank value) within a stated confidence limit. LOQ is the level above which quantitative results may be obtained with a stated degree of confidence.

Figure A3. Horwitz Curve, illustrating the exponential increase in the coefficient of variation as the concentration of the analyte decreases [ J. AOAC Int . 89, 1095(2006)].

© 2012 AOAC INTERNATIONAL

February 10-11, 2016

80