AOAC RI ERP Final Action Recommendations eBook

AOAC EXPERT REVIEW PANEL FOR MICROBIOLOGY FOR FOODS AND ENVIRONMENTAL SURFACES AOAC Expert Review Panel Final Action Feedback These factors were addressed in the OMA study considered by the ERP leading to first action OMA status for the method. The Probability of Detection is < 1 MPN for each of the matrices tested in validation studies, as evidenced by the fact that none of the >20 matrices tested demonstrated significantly better performance when comparing the POD for the appropriate reference culture method(s) and the POD for the BAX® System method. That is, each matrix studied indicated a limit of detection equal to that of the reference culture method as indicated by a dPOD whose confidence interval included zero when tested at a fractional level. ADDITIONAL FEEDBACK FROM USERS OF METHOD The BAX® System Real Time PCR Assay for Salmonella has had steadily increasing adoptions and sales since its initial first action status designation indicating robust method performance.

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