AOAC SPADA Meeting

AOAC INTERNATIONAL   Stakeholder Panel on Agent Detection Assays (SPADA)  Working Group Sessions – Wednesday, October 17, 2018  9:00 a.m. – 4:00 p.m. Conference Room 101 

Agenda 

I. Working Group Kickoff Meetings:  Bacterial Strain Verification Working Group   (9:00am – 12:00pm) 

a. Working Group Launch Presentation  i. Goals, timelines and rosters 

b. Background Presentations 

i. Shanmuga Sozhamannan, PhD, Tauri Group, JPEO JPM Guardian, DBPAO  ii. David Rozak, PhD, USAMRIID 

iii. Ian Gut, PhD, NBACC  iv. Katalin Kiss, PhD, ATCC 

c. Working Group Discussion 

i. Review the proposed outline of the project as presented   ii. Identify the minimum requirements needed to verify the species/strain of a culture.    With help of the contractor and WG chair, BSVWG will prepare a draft standard for verification of  bacterial strains to be presented to SPADA for consideration of approval at the second SPADA meeting 

II. Working Group Kickoff Meetings:   In‐Silico Analysis Working Group  (1:00pm – 4:00pm) 

a. Working Group Launch Presentation  i. Goals, Timelines and Rosters 

b. Background Presentations 

i. Shanmuga Sozhamannan, PhD, Tauri Group, JPEO JPM Guardian, DBPAO  ii. Jeff Koehler, PhD, USAMRIID  iii. Trevor Brown, PhD, JPM MCS/JPEO 

c. Working Group Discussion  

i. Review the proposed outline of the project as presented   ii. Identify the different steps that can be modified/eliminated from wet lab testing by  in silico PCR  analysis. The group will review and discuss features of the different databases and determine if  one or more shall be the focus of the standard setting effort  iii. Identify approaches for in silico analyses and potential software to use  iv. Determine the optimal settings for each  in silico PCR analysis setting  v. Discuss and determine how  in silico PCR analysis can fit into existing evaluation/validation  paradigm and prescribe the procedures of the use of  in silico PCR analysis  vi. Commence preparation of a draft standard to use  in silico PCR analysis to present to SPADA for  consideration of approval at the next SPADA meeting

V7                                                               10/12/2018

This agenda is subject to change without notice