AOAC SPADA Meeting
What would be an ideal strain characterization? e.g., rBaSwAT
VEGETATIVE CELLS • Phenotypic assays Microbiological tests
Phage sensitivity ( and AP50c) Antimicrobial resistance Spore formation Immunological tests (LFI, PR2, Magpix and Toxin Assay) • Genotypic assays Toxin deletion verification by PCR Optical mapping and Whole genome sequencing Molecular tests for signatures (PCR) SPORES • Production, purification and irradiation inactivation (using new protocol established by the working group) Physical properties Molecular and Immuno assays and bridging studies Animal studies Tab: ~$800K/~8 strains
2018_10_17_SPADA_Brief
UNCLASSIFIED
23
Critical Reagents Program Microbial Threat Information Center (CRPµTIC)
2018_10_17_SPADA_Brief
UNCLASSIFIED
24
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