AOAC SPADA Meeting

What would be an ideal strain characterization? e.g., rBaSwAT

VEGETATIVE CELLS • Phenotypic assays  Microbiological tests

 Phage sensitivity (  and AP50c)  Antimicrobial resistance  Spore formation  Immunological tests (LFI, PR2, Magpix and Toxin Assay) • Genotypic assays  Toxin deletion verification by PCR  Optical mapping and Whole genome sequencing  Molecular tests for signatures (PCR) SPORES • Production, purification and irradiation inactivation (using new protocol established by the working group)  Physical properties  Molecular and Immuno assays and bridging studies  Animal studies Tab: ~$800K/~8 strains

2018_10_17_SPADA_Brief

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Critical Reagents Program Microbial Threat Information Center (CRPµTIC)

2018_10_17_SPADA_Brief

UNCLASSIFIED

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