AOAC SPADA Meeting

3/11/2020

SIGNATURE SEQUENCE IDENTITIES OF THE TARGET SEQUENCES OF INC/EXC STRAINS IN SPADA PANELS

100% match between amplicon and target

99% match between amplicon and target  Unnecessary wet lab testing of assays in strains with perfect matches to the assays

3/12/2020

AOAC_SPADA_ISA_presentation

5

5

DELAYS IN OBTAINING REFERENCE MATERIALS FROM OUTBREAKS

Examples of the timeline for obtaining Ebola reference materials from Africa

 Delays in obtaining pathogen reference materials may hamper development of new and or ‘old and improved’ detection assays in response to discovery of signature erosion and make an impact in the field in a timely manner.

AOAC_SPADA_ISA_presentation

6

3/12/2020

6

3