AOAC SPDS ERP DECEMBER 15, 2017

III. Review of Information in Support of the Method

III. Review of Supporting Information 1. Are the definitions specified in the SMPR used and applied appropriately in the supporting documentation (manuscripts, method studies, etc...)? If not, please explain the differences and if the method is impacted by the difference. 2. Is there information demonstrating that the method meets the SMPR Method Performance Requirements using the Reference Materials stated in the SMPR? If not, then specify what is missing and how this impacts demonstration of performance of the method.

Reproducibility as defined in the SMPR is not carried out, but Intermediate Precision data is presented. LOQ is calculated based on an EPA MDL procedure which appears to be quite similar to the AOAC method.

All reference materials used conform to Tables 1 and 2 in the SMPR, with CBL being an additional cannabinoid from outside of the list.