AOAC SPDS Mid Year 2016

SMPR Key Points

– Reference method for cGMP compliance – Quantitation of each individual curcuminoid and  l l ti f th f i id ca cu a on o e sum o curcum no s – Method performance requirements:

Parameter

Requirement

Limit of Quantitation (LOQ)  (%)

≤ 0.1

Recovery (%)

97 – 103

Analytical Range (%)

≤ 0.1 – 50

> 50

% RSD r

≤ 4

≤2

% RSD R

≤ 6

≤ 3

SMPR Key Points

Possible Interferences

– Piper nigrum – Zingiber officinale (ginger) – Capsicum annuum (cayenne pepper) –  ‐carotene – Lutein – Lycopene – Zeaxanthin