AOAC SPDS Mid Year 2016

Existing Methods • 1 H NMR Spectroscopic Method – B. Diehl & E. E. Teichmuller, Aloe vera , Quality and Identification,  SOFW‐ Journal 1997 , 123 , Jahrgang, 1015‐1018.  – Bozzi et al ., Quality and authenticity of commercial aloe vera gel  powders.   Food Chem ., 2007 , 103, 22‐30. – B. Davis & W. J. Goux, Single‐Laboratory Validation of an NMR Method for  the Determination of Aloe Vera Polysaccharide in Pharmaceutical  Formulations,  J. of AOAC International. 2009 , 92 , 1607‐1616. 1 – Jiao et al . Quantitative H‐NMR Spectrometry Method for Quality Control  of Aloe vera Products.  J. of AOAC International , 2010 , 93 , 842‐847. – J. Edwards in Aloe Vera Leaf, Aloe Vera Leaf Juice, and Aloe Vera Inner leaf  Juice, Aloe vera (L.) Burm. f. Standards of Identity, Analysis, and Quality  Control . R. Upton   et al . Eds.   American Herbal Pharmacopeia 2012, pp  33‐42.

Existing Methods • 1 H NMR Spectroscopic Method

Nicotinamide

Glucose

Malic acid

Citric acid

Isocitric acid

Isocitric acid lactone

acid

β-Glucose c acid

ric acid

d lactone

cid lactone

olysaccharides (Acemannan) actic acid

se

L

Mali

Isocit

Isocitric

α-Gluco

Acetyl p

Isocitric a

Fructose

Isocitric aci

Acetic acid