AOAC SPDS Set 2 ERP

6. Based on the supporting information, what are cons/weaknesses of the method? Cons/weaknesses: detection method, only mitragynine is quantified 7. Any general comments about the method? The proposed method is simple but may be critical on the fact of the detection at 226 nm which could, may be also detect other compounds than the target one. The other drawback of the proposed method is that it allows the quantification of only mitragynine. V. RECOMMENDATION FOR THE METHOD: Do you recommend this method be adopted as a First Action and published in the Official Methods of Analysis of AOAC INTERNATIONAL? If no, please specify rationale. I do not recommend this method be adopted as a First Action and published in the Official Methods of Analysis of AOAC INTERNATIONAL taking into account the following points:  The applicability of the proposed method does not support that of the SMPR  The used detection method is not specific  The method does not meet the minimum acceptance criteria given in the SMPR  The method does not contain any system suitability tests and/or analytical quality control as specified in the SMPR.  The method is not well written

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