AOAC SPDS Set 2 ERP

Method Review Form

AOAC INTERNATIONAL Standards Development

Name of Reviewer: Catherine (Kate) Rimmer Title of Method: LC/MS Method for the Identification of Mitragyna speciose (Kratom) and Quantitation of Mitragynine Using Linear Ion Trap Mass Spectrometer

AOAC Candidate Method Number: KRA-04

Applicable SMPR : SMPR 2015.008

I.

SUMMARY OF METHOD

This method is an LC/MS method for the determination of mitragynine mass fraction and the identification of Mitragyna speciosa. For the identification several of the alkaloids are separated.

II.

REVIEW OF THE METHOD ONLY: 1. Does the applicability of the method support the applicability of the SMPR? If no, please explain what is missing.

Yes

2. Does the analytical technique(s) used in the method meet the SMPR? If no, please specify what how it differs from what is stated in the SMPR.

Yes, all methods are acceptable for the SMPR.

3. Are the definitions specified in the SMPR used and applied appropriately in the method? If no, please indicate how the terms are used.