AOAC SPIFAN ERP Meeting Book-March 16, 2016

VitK-01 w/SLV FOR ERP USE ONLY DO NOT DISTRIBUTE

Silliker Chem, Res. Center Crete, IL – Validation of a LC-MS/MS Method for Vitamin K Analysis

0.4 4.5

0.0 0.0

0.4 4.0

Sample #6

Stdev

% RSD

2

2

2

n

Mean

1.7 0.0 1.5

1.0 0.0 3.0

2.7 0.0 1.8

Stdev

SPIFAN Sample #7

% RSD

2

2

2

n

Mean Stdev

5.9 0.9

1.0 0.2

6.9 1.1

SPIFAN Sample #8

15.8

15.3

15.7

% RSD

2

2

2

n

Mean

6.6 0.3 4.8 2.3 0.0 2.2 2.2 0.2 8.5 6.9 0.2 2.8 4.6 0.2 4.5 5.4 0.3 4.8 7.6 0.1 1.8 6.4 0.5 7.7 7.9 0.6 7.4 3 3 3 3 3 3 3 3

1.0 0.1

7.5 0.5 6.4 2.6 0.1 2.4 2.6 0.2 8.1 7.8 0.2 2.8 5.6 0.2 4.4 6.5 0.3 4.9 9.0 0.1 1.1 8.4 0.6 7.6 3 3 3 3 3 3 3

Stdev

SPIFAN Sample #9

12.5

% RSD

3

n

Mean

0.3 0.0 3.7 0.4 0.0 5.8 0.9 0.0 5.5 1.0 0.0 4.3 1.1 0.1 5.2 1.5 0.0 2.7 2.0 0.1 7.2 2.8 0.1 2.6 3 3 3 3 3 3 3

Stdev

SPIFAN Sample #10

% RSD

n

Mean

Stdev

SPIFAN Sample #11

% RSD

n

Mean Stdev

SPIFAN Sample #12

% RSD

n

Mean

Stdev

SPIFAN Sample #13

% RSD

n

Mean

Stdev

SPIFAN Sample #14

% RSD

n

Mean

Stdev

SPIFAN Sample #15

% RSD

n

Mean

Stdev

SPIFAN Sample #16

% RSD

3

n

Mean

10.7

0.7 6.2

Stdev

SPIFAN Sample #17

% RSD

3

3

3

n

Silliker Laboratories, Chemistry Research Center, Date: 1/30/15

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