AOAC SPIFAN Nutrients ERP-Final Review (Oct. 2018) Pubs

2011.06 (September 2017)-Fol-22 MLT Report

FOR ERP USE ONLY DO NOT DISTRIBUTE

Table of Contents

Section

Description

Page

Summary

3 3 3 3 3 3 3 4 4 4 4 4 5 5 5 7 8 8 8 8

1

Introduction Study Title

1.1 1.2 1.3 1.3 1.4 2.1 2.2 2.3 2.4 2.5 3.1 3.2 3.3 4.1 4.2 4.3 2 3 4

Study Objective Study Director

Associate Study Director Author of the MLT Report

Study Design

The MLT Overview

Method Set up and Qualification of Participants Multi-laboratory testing by qualified participants

Reporting

Statistical Evaluation Materials and Methods

Study Samples MLT Participants Analytical Method

Results and Discussion

Overview

MLT Results and Statistical Evaluation

Method Precision Method Accuracy Method Applicability

13 19 20 20 20 20 21 21 21 21 22

5 6 7 8 9

Contribution of folates other than folic acid

Safety Considerations

Comments from Collaborators

10 11 12 13

Conclusions

Recommendations

References

Acknowledgements Appendix -1: Method

Collaborative Study Report: Method AOAC 2011.06 (Folate by LC-MS/MS) 2