AOAC SPIFAN Nutrients ERP Report (July 26, 2022)

I. WELCOME AND INTRODUCTIONS KaterinaMastovska welcomed all participants to the ERP meeting and the ERP members were introduced.

II. REVIEWOF METHODS BY EXPERT REVIEW PANEL (ERP) FOR FIRST ACTION OFFICIAL METHOD SM STATUS For each method, the ERP reviewed and discussed method(s) submitted for First Action Official Method SM status.

Method Title

Reviewer(s)

Vote

Method

Comments

CHLORATE / PERCHLORATE

Motion: To accept the ERP requirements for method authors to complete for reconsideration of the method for First Action Official Methods SM status Melissa Phillips proposed & Jayesh Gandhi second

Marina Torres Rodriguez Melissa Phillips J. Fernando Huertas Pérez

See requirements below

Chlorate-01 – Method for the Determination of Chlorate and Perchlorate in Baby Food, Baby Food Ingredients, Infant Formula and Infant Formula Ingredients by Liquid Chromatography – Tandem Mass Spectrometry: Single Laboratory Validation

Unanimous

CHLORATE-01 ERP REQUIREMENTS: 1. For infant formula provide additional example chromatograms at the LOQ level for different infant formula products 2. For meat and baby food, try to improve signal to noise at the target LOQ level 3. Provide RSDs and mean recoveries for each analyte, matrix and concentration level combination (see Excel table) 4. Determine LOQs according to the SMPR validation guidance at the lowest spiking level that meet the recovery and RSD requirements 5. For baby food provide validation data for each representative matrix separately (cereal based, fruit/vegetable based & meat based)

6. Label chromatograms with the actual spiking concentrations 7. Update the reference material codes in the manuscript

Motion: to accept these requirements/recommendations Melissa Phillips motioned & Jayesh Gandhi second