AOAC SPIFAN Nutrients ERP Report (March 14, 2023)

I.

WELCOME AND INTRODUCTIONS Darryl Sullivan welcomed all participants to the ERP meeting and the ERP members were introduced along with roll call.

II. REVIEW OF METHODS BY EXPERT REVIEW PANEL (ERP) FOR FIRST ACTION OFFICIAL METHOD SM STATUS For each method, the ERP reviewed and discussed method(s) submitted for First Action Official Method SM status. NEXT STEPS/FEEDBACK FROM EXPERT REVIEW PANEL Darryl Sullivan provided next steps including recommendations from the Expert Review Panel to method authors including providing comparison data with the Willard Winter procedure. In addition, schedule a meeting to discuss the methods that have already received First Action Official Method SM status for HMO and Fluoride. The proposed meeting will be scheduled in conjunction with AOAC Analytical Methods Week (AMW) “Spring” session. III.

Fluor-04 Fluor-05 Fluor-06

Abbott Nutrition

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Mérieux NutriSciences

Triskelion

REVIEW OF METHODS: A1/A2 BETA CASEIN

CODIFICATION: A1BC-01 METHOD TITLE: Determination of A1- and A2- type β -casein in infant formula, adult/pediatric formula and select milk and milk products by Capillary zone electrophoresis (CZE) REVIEWERS: Tom Vennard & Christophe Fuerer MOTION: No action taken - method not recommended for First Action Official Methods SM status

9 Yes/0 No/ 0 Abstain RECOMMENDATION: •

Include bullet points from Reviewer 2 assessment.

• Be able to perform/demonstrate method sensitivity in complex matrix • Reference standards need to be identified & definitions on how their used • Current method range needs to be defined o Section Ee

Motion to approve recommendations: Tom Vennard motioned & Christophe Fuerer second Vote: 9 Yes/0 No/0 Abstain