AOAC SPIFAN Stakeholder Program Meeting Book (August 27, 2022)

Infant and Adult Formula and Breastmilk

• Direct analysis of samples is best • Direct analysis needs to separate inorganic and organic fluorine • Matrix effects need to be accounted-for

• Method requirements:

• Minimal background interference • Direct, quantitative measurement of F - • No accounting for matrix effects • Reproducible and accurate • 19 F NMR has shown this is possible in environmental PFAS measurements

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