AOAC SPIFAN Stakeholder Program Meeting Book (August 26, 2023)

Method comparison study in 2022-Osmolality Methods • No international method • New GB 25596, drafted with BJS202102(Freezing Point Depression method) as basis Discussion

• Freezing Point Depression might be inappropriate to measure osmolality of viscous products /high concentrations nutritional formulas. • The guideline for the use of Freezing Point Depression and Vapor Pressure Depression method. • Plan for AOAC standard development of Osmolality. Progress • Vapor Pressure Depression was adopted in GB method • GB drafter conducted the experimental comparison studies of two methods .