AOAC SPIFAN WPC ERP-Final Action Review (Nov. 2017)

2016.15 (Nov. 2017) - WPC-31 MLT-Final Action Review

FOR ERP USE ONLY DO NOT DISTRIBUTE

Table 2016.15H. Statistical analysis of the test data for the 15 sample pairs

SPIFAN 1

SPIFAN 2

SPIFAN 3

SPIFAN 4

SPIFAN 5

19 38

19 38

19 38

19 38

19 38

Total number of laboratories Total number of replicates

p

Sum(n(L)) XBARBAR

56.35

41.54

65.28

42.72 1.50 2.54 3.51 5.94 2.27 2.62 N/S 32 **

60.50

Overall mean of all data (grand mean) Repeatability standard deviation Reproducibility standard deviation Repeatability relative standard deviation

0.94 1.77 1.67 3.14 2.18 1.44

0.88 1.75 2.11 4.22 2.28 1.85 N/S

0.94 1.42 1.44 2.18 2.13 1.02 N/S

1.28 1.43 2.11 2.37 2.16 1.11 N/S

s(r) s(R)

RSD(r)

Reproducibility relative standard deviation RSD(R)

Horwitz RSD HORRAT value Outlier test* Declared Value

RSDH

HorRat

17 C

53

40

65

60

106

104

100

134

101

% of Declared value

Formula 1

Formula 2

Formula 3

Formula 4

Formula 5

19 38

18 36

19 38

19 38

19 38

Total number of laboratories Total number of replicates

p

Sum(n(L)) XBARBAR

49.99

63.63

73.24

68.92

69.26

Overall mean of all data (grand mean) Repeatability standard deviation Reproducibility standard deviation Repeatability relative standard deviation

0.82 1.78 1.63 3.57 2.22 1.61 N/S

0.58 1.51 0.92 2.37 2.14 1.11 N/S > 60 106 #

0.61 1.68 0.83 2.30 2.10 1.10

1.15 1.78 1.67 2.59 2.12 1.22 N/S

1.26 2.22 1.82 3.20 2.11 1.51

s(r) s(R)

RSD(r)

Reproducibility relative standard deviation RSD(R)

Horwitz RSD HORRAT value Outlier test* Declared Value

RSDH

HorRat

2+16 DG

17 C

50

70

70 98

70 99

100

105

% of Declared value

Formula 6

Formula 7

Formula 8

Formula 9

Formula 10

19 38

19 38

19 38

19 38

19 38

Total number of laboratories Total number of replicates

p

Sum(n(L)) XBARBAR

63.40

69.41

64.92

60.56

62.36

Overall mean of all data (grand mean) Repeatability standard deviation Reproducibility standard deviation Repeatability relative standard deviation

1.32 2.11 2.09 3.33 2.14 1.55 N/S > 60 106 #

1.09 2.00 1.57 2.89 2.11 1.37

0.65 1.58 1.01 2.43 2.13 1.14 N/S

0.89 1.58 1.47 2.61 2.16 1.21 N/S

1.01 1.72 1.61 2.76 2.15 1.29 N/S

s(r) s(R)

RSD(r)

Reproducibility relative standard deviation RSD(R)

Horwitz RSD HORRAT value Outlier test* Declared Value

RSDH

HorRat

17 C

70 99

60

60

60

108 104 *C: Cochran test; SG: Single Grubbs test; DG: Double Grubbs test. No more outliers after removal. Outliers were kept in the statistical evaluation. ** whey content of NIST SRM 1849a (32%) is based on formulation details, the rest is casein. # Calculated based on a declared value of 60%. 101

% of Declared value