AOAC SPSFAM Cannabis Concentrates SMPR v2.docx

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Reproducibility 

The standard deviation or relative standard deviation calculated from among‐laboratory data. 

Expressed as the reproducibility standard deviation (SD R

); or % reproducibility relative standard 

deviation (% RSD R

). 

Recovery 

The fraction or percentage of spiked analyte that is recovered when the test sample is analyzed 

using the entire method. 

5. Method Performance Requirements :   

See table 2 and 3. 

6. System suitability tests and/or analytical quality control:

Suitable methods will include blank check samples, and check standards at the lowest point and 

midrange point of the analytical range. 

7. Reference Material(s):

See tables 1A and 1B for sources of reference materials. 

Refer to Annex F: Development and Use of In‐House Reference Materials  in Appendix F: Guidelines  for Standard Method Performance Requirements , 19 th  Edition of the AOAC INTERNATIONAL Official  Methods of Analysis (2012).  Available at:  http://www.eoma.aoac.org/app_f.pdf 

8. Validation Guidance :   

Appendix D : Guidelines for Collaborative Study Procedures To Validate Characteristics of a Method  of Analysis; 19 th  Edition of the AOAC INTERNATIONAL Official Methods of Analysis (2012).  Available 

at:  http://www.eoma.aoac.org/app_d.pdf 

Appendix F :  Guidelines for Standard Method Performance Requirements; 19 th  Edition of the AOAC 

INTERNATIONAL Official Methods of Analysis (2012). Available at:  

http://www.eoma.aoac.org/app_f.pdf 

Appendix K : Guidelines for Dietary Supplements and Botanicals; 19 th  Edition of the AOAC  INTERNATIONAL Official Methods of Analysis (2012).  Available on line at: 

http://www.eoma.aoac.org/app_k.pdf

9. Maximum Time‐To‐Result:   None

Table 1A:  Required Cannabinoids 

Common  Name  

Abbrev ‐iation 

IUPAC Name 

CAS  Number 

Molecular  Structure 

Reference   Material  Restek  Cerilliant 

Cannabidiol 

 CBD 

13956‐29‐1 

2‐[(1 R ,6 R )‐6‐isopropenyl‐3‐ methylcyclohex‐2‐en‐1‐yl]‐5‐ pentylbenzene‐1,3‐diol 

Sigma‐Aldrich  API Standards  Echo Pharm  Lipomed AG

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