AOAC SPSFAM March 16 2015 eBook

Reproducibility .—The standard deviation or relative standard deviation calculated from 49 among-laboratory data. Expressed as the reproducibility standard deviation (SDR); or % 50 reproducibility relative standard deviation (%RSDR). 51 52 Recovery .—The fraction or percentage of spiked analyte that is recovered when the test 53 sample is analyzed using the entire method. 54 55 Total Inorganic Arsenic- The sum of arsenite and arsenate either reported as the sum of the 56 individual species or converted into one form and reported as the total.

57 58 59 60 61 62 63

5 Method Performance Requirement s

See table 3.

6 System suitability tests and/or analytical quality control 64 65 Suitable methods will include blank check samples, and check standards at the lowest point 66 and midrange point of the analytical range, and a protocol to demonstrate suitability.

67 68 69 70

7 Reference Material(s

Refer to Annex F: Development and Use of In-House Reference Materials in Appendix F : 71 Guidelines for Standard Method Performance Requirements [19 th Edition of the AOAC 72 INTERNATIONAL Official Methods of Analysis (2012]. Available at: 73 http://www.eoma.aoac.org/app_f.pdf 76 77 Validation data must include at a minimum arsenite and arsenate, or total inorganic arsenic, in 78 the food types listed in table 1 that apply to the candidate method for First Action Official 79 Methods of Analysis approval. It is not required to represent every arsenic species or food type. 80 81 Appendix D : Guidelines for Collaborative Study Procedures To Validate Characteristics of a 82 Method of Analysis; 19 th Edition of the AOAC INTERNATIONAL Official Methods of Analysis 83 (2012. Available at: http://www.eoma.aoac.org/app_d.pdf 74 75 8 Validation Guidance

84 85 86 87 88 89 90 91 92 93 94

9 Maximum Time-To-Result

No maximum time to result.

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