AOAC SPSFAM PAC ERP

4. Based on the supporting information, is the method written clearly and concisely? If no, please specify the needed revisions. 5. Based on the supporting information, what are the pros/strengths of the method? 6. Based on the supporting information, what are the cons/weaknesses of the method?

No. The method was not easy to follow and does not contain important method information such as instrument operation parameters.

This method is articulate and robust on estimating ratios of A- to B-type bonds in cranberry proanthocyanidin.

This method was not written and validated in a format that is required by the AOAC SMPR 2017.004. The method did not test all types of matrices listed in Tier 1 of Table 3 in the SMPR. Authors did not validate this method based on the probability of identification model that is required according to the AOAC validation guidance appendix K. The method has the potential to be used to identify the presence of Type-A proanthocyanidin in cranberry. However, because of above-mentioned flaws, the current method is not recommended to be adopted as an AOAC First Action Official Method.

7. Any general comments about the method?

Recommendation for the Method

V. Final Recommendation Do you recommend this method be adopted as a First Action and published in the Official Methods of Analysis of AOAC INTERNATIONAL? Please specify rationale.

No.

I do not recommend this method to be adopted as a First Action because it does not have enough data to meet SMPR validation guidance and method performance requirements.