Amino Acids Working Group Meeting Book (July 3, 2018)

Infant Formula Energy and Amino Acid Guidance EU Codex FSANZ

GB 60 70

60 70

60 70

60 75

Minimum Maximum

Energy (kcal/100 mL)

Amino Acid Cys(CSSC)

Minimum mg/100kcal

38 a

38 a

25 c

24 a

His

40 90

41 92

50 88

36 90

Ile

Leu Lys Met Phe

166 113 23 a 83 b

169 114 24 a 81 b

176 126

162 105 20 a 54 b

79-(Cys+CSSC) e

71 d

Thr Trp Tyr Val

77 32

77 33

79 29

75 33

76 b

75 b

134-Phe e

60 b

88 93 a If Met:Cys(CSSC) < 2, Cys(CSSC) and Met may be added to meet appropriate total (EU = 61, Codex = 62, GB = 44) b May be combined to meet total (EU = 159, Codex = 156, GB = 114) c 25 is for Cys+CSSC, Cys + CSSC + MEt < 79 d 71 is for Phe, Phe + Tyr < 134 e No explicit minimum 90 105

Amino Acid Minimum Levels based on Guidance

mg/ 100 mL

EU

Codex

FSANZ

GB

Amino Acid

at Low Energy Limit

at High Energy Limit

at Low Energy Limit

at High Energy Limit

at Low Energy Limit

at High Energy Limit

at Low Energy Limit

at High Energy Limit

14 22 54 97 63 12 32 45 20 36 56

Cys(CSSC)

23 24 54 68 14 50 46 19 46 53

27 28 63 79 16 58 54 22 53 62

23 25 55 68 14 49 46 20 45 54

27 29 64 80 17 57 54 23 53 63

15 30 53

19 38 66

17 25 63 74 14 38 53 23 42 65

His

Ile

116

101

118

105

132

114

Leu Lys Met Phe

100

75

94

0

0

43 48 18

53 60 22

Thr Trp Tyr Val

0

0

63

78