Candidates for 2016 ERP of the Year

ERP PROFILE SUMMARIES

Primary and Secondary Evaluation of Method SJW-14

SJW-14:

Chemical Composition of Hypericumrumeliacum BIOSS. Essential Oil.A new Chemotype of This pharmologicallyvaluble species?

Chemistry & Biodiversity – Vol. 9 (2012), Niko S. Radulovic´* and Polina D. Blagojevic

Author(s):

S UMMARY OF M ETHOD : G ENERAL C OMMENTS :

The method presented results dealing with the extraction of the essential oil of Hypericum rumeliacum aerial parts and analysis of its constituents through GC and GC/MS techniques. The results were used with MVA to determine if there are chemo type differences that exist within H. rumeliacum.

P ROS /S TRENGTHS : This method used nitrogen to evaporate solvent which reduces loses of volatiles.

C ONS /W EAKNESSES : This method pertains to only plant tissues and not supplements. It’s used for H. rumelaicum, not St. Johns Wort (H. perforatum). This is not a quantitative method and is not applicable to the SMPR.

EXPERT REVIEW PANEL VOTE AND RECOMMENDATION

MOTION: Not to consider this method for First Action Official Method status. Es-Safi, Mudge (Unanimous) Motion Passed

96