DRAFT AOAC SMPR 2018.XXX; Version 6, July 10, 2018 1 2 Method Name: 3
Identification and Quantitation of Selected Pesticide Residues in Dried
Intended Use : 6 7 1. Purpose: AOAC SMPRs describe the minimum recommended performance characteristics to be 8 used during the evaluation of a method. The evaluation may be an on-site verification, a single- 9 laboratory validation, or a multi-site collaborative study. SMPRs are written and adopted by AOAC 10 Stakeholder Panels composed of representatives from the industry, regulatory organizations, 11 contract laboratories, test kit manufacturers, and academic institutions. AOAC SMPRs are used by 12 AOAC Expert Review Panels in their evaluation of validation study data for method being considered 13 for Performance Tested Methods or AOAC Official Methods of Analysis , and can be used as 14 acceptance criteria for verification at user laboratories. Consensus-based Reference method.
The fraction or percentage of spiked analyte that is recovered when the test sample is analyzed
using the entire method.
5. Method Performance Requirements :
See table 2 and 3.
6. System suitability tests and/or analytical quality control:
Suitable methods will include blank check samples, and check standards at the lowest point and
midrange point of the analytical range.
7. Reference Material(s):
Refer to Annex F: Development and Use of In-House Reference Materials in Appendix F: Guidelines for Standard Method Performance Requirements , 19 th Edition of the AOAC INTERNATIONAL Official Methods of Analysis (2012). Available at: http://www.eoma.aoac.org/app_f.pdf
8. Validation Guidance :
Appendix D: Guidelines for Collaborative Study Procedures To Validate Characteristics of a Method of Analysis; 19 th Edition of the AOAC INTERNATIONAL Official Methods of Analysis (2012). Available
Appendix F: Guidelines for Standard Method Performance Requirements; 19 th Edition of the AOAC
INTERNATIONAL Official Methods of Analysis (2012). Available at:
Appendix K: Guidelines for Dietary Supplements and Botanicals; 19 th Edition of the AOAC INTERNATIONAL Official Methods of Analysis (2012). Available on line at:
U.S. Food and Drug Administration: Bioanalytical Method Validation Guidance for Industry, May
European Commission Guidance Document on Analytical Quality Control and Method Validation Procedures for Pesticide Residues and Analysis in Food and Feed (SANTE/11813/2017)