Carn-06_Book_Final

Carn-06 - Validation Report FOR ERP USE ONLY DO NOT DISTRIBUTE

made for every batch and that relative difference (daily average vs. overall aver- age) is low this is seen as being acceptable. For Carnitine the RSD% will be set to 5% for carnitine.

Trueness:

The methods trueness has been evaluated by analysing reference material. Reference materials: Reference materials with values on carnitine exist or are at the moment under testing for certification. We have analysed the certified reference material SRM 1849A (Infant/adult nutri- tional formula), SRM 1546 (Meat Homogenate) and SRM 1845A (Whole Egg

powder, under certification). Sample: NIST SRM 1849A Matrix: Infant/adult nutritional formula. Species Result (m) carnitine 140 ± 2 mg/kg 4 136 ± 14 mg/kg

n Reference value (CRM) k Comment

2 free The certified values have been evaluated according to ERM application Note 1. 1 Example of the calculation: The certified content of free carnitine is (136 ± 14) mg/kg, k = 2,00. The SRM 1849a was analysed 4 times. (140 ± 2) mg/kg.

If Δ m ≤ U Δ then no significant difference between the measurement result and the certified value has been demonstrated.

1 http://irmm.jrc.ec.europa.eu/html/reference_materials_catalogue/user_support/index.htm.