Chemistry-PTM-OMA_Modules_1-4

Overview Parameters are varied and deviations tested by an appropriate  experimental design: • Plackett‐Burman design (e.g., 7 parameters, 8 treatments) • Full factorial design (k parameters, 2 k   treatments, e.g., 3 parameters, 8  treatments) • Fractional factorial design of choice, 2 k‐1 or  2 k‐2  (k=4‐6 parameters)