Chemistry-PTM-OMA_Modules_1-4

Factorial Design

• Full factorial design • For selected parameters, vary conditions above and below nominal test  conditions • Test every possible combination of all variables • Requires 2 n  de terminations, where n is the number of parameters varied • Fractional factorial design • For selected parameters, vary conditions above and below nominal test  conditions • Test a subset of a full factorial design depending upon the fractional design  (e.g.,  ½,  ¼) • Study materials prepared in the same manner as the matrix study materials