Chemistry-PTM-OMA_Modules_1-4

Fractional Factorial Design  (6 variables, 2 4‐2  factorial design ‐ 1/4  fraction resulting in 16 determination) Determination # 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 A a A a A a A a A a A a A a A a B B b b B B b b B B b b B B b b Parameter

A or a B or b C or c D or d E or e F or f

C C C C c c c

c

C C C C c c c c

D D D D D D D D d d d d d d d d

E e e E e E E e E

e e E e E E e

F F f

f

f

f

F F

f

f

F F F F f

f

Observed Result

k l

m n o p q r

s

t

u v w x y z

p