GOS Working Group Meeting Book (November 29, 2017)

Analyte Definition (GOS)

• Implications: Candidate methods must be able to fully account for the large variety of different GOS structures produced during transgalactosylation in the presence of potentially interfering substances such as free monosaccharides, lactose, etc.

Specific Performance Claims

Analytical Range: 0.2 – 5.0 g/100g * Limit of Quantitation (LOQ): ≤ 0.2 g/100g *

Recovery: 90 - 110% Repeatability : (RSDr) ≤ 6% Reproducibility : (RSDR) ≤ 12%

* g/100g in reconstituted final product: - Ready to feed liquids “as-is” - Reconstituted powders (25 g into 200 g water) - Liquid concentrates diluted 1:1 by weight