Quant. MAC Working Group Meeting Book (March 13, 2019)
AOAC Annual Meeting 2018
• The two step approach allows for secondary evaluation of the method in cases of non- homogeneity of the sample based on the reference method
AOAC Annual Meeting 2018
1.1
bias β-ETI lower β-ETI upper
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AL AL
ALs ALs
-1.1
Comparison
y = 0.9933x - 0.01
Large s for alternative and reference. No bias.
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Initial AP Æ reject Current AP Æ accept
Alternative
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Reference
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