ISPAM Working Group Chair Presentation Book

Targeted MS Analysis l ifi di i

f d d/ • Ana yte‐spec c con t ons or ata acqu s t on an or  data analysis • Typically SIM or MS/MS (MRM) analysis  • Known chromatographic behavior (retention times) and  MS data (MS or MS/MS spectra and ion ratios) • Screening of known adulterants • Quantitative analysis for compounds with reference  standards i i i

Example: ‐ Lee et al., J. Pharm. Biomed. Anal. 83 (2013) 171– 178  (38 PDE5 i hibi )  n tors