ISPAM Working Group Chair Presentation Book

Adulteration of Dietary Supplements  with Synthetic PDE5 Inhibitors

• Serious problem i l i

d ( l h l) h l h ff – Potent a ser ous a verse even et a ea t a ects – Adulteration with approved drugs but also their  unapproved analogs (unknown toxicological effects) – High incidence of adulteration

Campbell et al .,  J. Sex. Med. 10 (2013) 1842‐1849: ‐ 81% out of 91 tested herbal products adulterated  with synthetic PDE5 inhibitors and their analogs