ISPAM Working Group Chair Presentation Book

SMPR Key Points:  Screening Method

Minimum  Acceptable   R lt esu s

Target Test  Concentration

Parameter Parameter Requirements

Minimum of 33 replicates  per matrix type, spiked at 

100 ppm 

POD  @ low 

90% POD §

concentration or below the designated  low level target test conc.

n

Minimum of 5 replicates  per matrix type spiked at  10x the designated low  level target test conc.

y Validatio

POD @ high  concentration 

10 x  low conc. 100% correct  analyses are

Laborator

expected per  matrix type

POD @ zero 

Minimum of 5 replicates 

Single 

0 ppm

concentration per matrix type. 

§ 95% confidence interval