July 2019 PAC ERP Review Book

Proanthocyanidins in Cranberry and Cranberry Products:   Method Reviews and Decisions

AOAC  Method # 

Manuscript Title, Submitter and Reviewers 

ERP Decisions / Consensus 

Title:   Deconvolution of matrix‐assister laser  desorption/ionization time‐of‐flight mass spectrometry  (MALDI‐TOF MS) for identification of A‐type  proanthocyanidins in cranberry based foods and dietary  supplements  Author(s): Christian G. Krueger and Jess D. Reed 

MOTION to move this method to First Action Official Methods of Analysis ® Status  (You/Mudge)   0 in favor, 8 opposed, 2 abstentions.  The motion failed.  Reasoning/Summary: Although the ERP members stated that this method does, in general, meet the SMPR,  the ERP requests that additional data and clarity be provided prior to granting First  Action Official Methods of Analysis  status. ____________________________________________________________  First Action Requirements: 

Submitted by: Christian G. Krueger  Primary Reviewer:   Kate Rimmer, NIST Secondary Reviewer:   Hong You, Eurofins

 Include all Tier 1 products from Table 3 of SMPR.  Present data from selectivity study mandated in Table 2 of SMPR.  Provide clear method performance parameters.

MOTION to accept the First Action Official Methods of Analysis  recommendations  and suggestions as presented (Mudge / You).  7 in favor, 0 opposed, 2 abstentions.  The motion passed.

                 PAC‐01

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